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(850) 654-5222 or (866) 701-7088 toll free

"Come see why we travel from so far away to see Dr. Grisoli"

Voted "Best Vein Center on the Emerald Coast" by Northwest Florida Daily News with 50,000 subscribers

"His attention to detail is why he is the only vein doctor I see."

The American Board of Phlebology offers certification in the specialty of phlebology. Phlebology is the medical specialty that deals specifically with venous disease. Certification demonstrates that physicians have met rigorous standards of education, experience, and evaluation. In order to become a Diplomate of the American Board of Phlebology, a phlebologist must be a physician and:

  • Complete the requisite training or experience qualifications
  • Meet the continuing medical education requisites
  • Pass a certification examination

Dr. Grisoli was the first  physician in the four most western counties of Florida (Escambia, Santa Rosa, Okaloosa, and Walton) to receive certification by the American Board of Phlebology. He is currently the only physician in the United States Board Certified in Anesthesiology, Critical Care Medicine, and Phlebology. This means that even if you have serious medical problems, he can safely treat your vein condition and safely manage to keep you free of pain during the procedure.  Before consenting to vein treatment by any physician, it is worth discovering if that physician is certified by the American Board of Phlebology. For a listing, please follow the link below.

     Toll Free 1-800-VARICOSE


If you suffer from problems related to varicose and spider veins, you are not alone. It is estimated that more than 80 million Americans suffer from some form of venous disorder. Dr. Grisoli utilizes both laser treatment as well as injections (sclerotherapy) in the treatment of leg veins, breast veins, buttock veins, hand veins, and facial veins. Each has a specific application.

In addition to leg veins, there is almost no area of the body on which we have not treated either varicose or spider veins. After leg veins, the most commonly treated body areas are the breasts, chest, buttocks, temples, face, forehead, hands, and spider veins on the neck and back. Vaginal varicosities, which may follow pregnancy, are also treated. These veins heal rapidly and results of their treatment are excellent. Prominent veins in the temple area often follow facial reconstructive surgery and unsightly breast veins are frequently seen after breast augmentation. These veins may detract from an otherwise perfect cosmetic result. Treating them provides the “finishing touch”. When temple veins are treated, there may be short-term bruising and edema (swelling) around the eye. It must be emphasized that veins around the eye are separate and distinct from veins in the skull, and that vein therapy in the area of the eye can be safely performed.

While some people seek treatment for cosmetic improvement, many seek relief from pain. Help is available for both.

The following information is for the cosmetic treatment of spider veins and small varicose veins.  Note: We are a comprehensive leg vein treatment center and if you have large bulging veins or “grape-like” clusters (that give you medical concern) then proceed to the portion of this website called “Large Veins”.

 Steps to my treatment:

Step 1

Call the Destin Vein Center at 850-654-5222 or toll free 1-800-VARICOSE to schedule a 15 minute complimentary consultation with Dr. Grisoli. By Dr. Grisoli’s request, you will be asked for a convenient time at which his assistant can call you.
Step 2

Expect a phone call, at your convenience, by Dr. Grisoli’s assistant prior to your consult to answer any questions you may have. Arrive at your consult with a pair of shorts or loose clothing to change into so that you are comfortable and able to demonstrate to Dr. Grisoli your areas of concern.

Step 3

At your consult you will be given a treatment plan which addresses both medical and cosmetic concerns depending on your particular needs. “Sclerotherapy” is the best method of treatment of spider and uncomplicated bulging veins. Your treatment will involve injection of a solution directly into the problematic veins. The tiny spider veins as well as some of the larger ‘bulging’ veins are treated in this way. 

 We want you to be comfortable during your treatment so several options of pain control will be discussed at this time:

A)    The average patient may be given a prescription for pain medication to be taken one hour prior to the procedure. (You must have someone drive you to your appointment if you choose this option).

B)    Other patients opting not to take the pain medication will be instructed to use over- the- counter pain relievers prior to their appointment (something you would normally take for headache pain).

C)    The third option is to take nothing at all and some patients are quite comfortable with this option.

The procedure will likely involve multiple tiny ‘needle-sticks’. The needle is the smallest one made and the solution does not burn or sting. You should have no discomfort after the procedure and should need no further medication. 

Step 4

The day of your procedure arrive with your shorts into which you will change. Dr. Grisoli will treat the front and back of both legs. Your appointment should last 30 minutes. Upon completion of the sclerotherapy you will put on light support hose, dress in your regular clothes and resume your normal day’s activities. We offer either pantyhose or thigh-high hose in nude or black. If you have not taken the prescription medication you may go back to work. It is not necessary or desirable to recline or elevate your legs on this day.

Step 5

For the next week, you will wear the light support hose during the day. You may take them off to sleep at night. To maximize the benefit of your procedure we suggest that you not submerge your legs in hot water (bathtub or hot tub) or vigorously exercise them for one week. Normal showers are acceptable and so are upper body workouts. Upper body workouts designed for cardio-conditioning are also perfectly acceptable.

Step 6

To completely clear your legs of spider and varicose veins may take 2-3 treatments depending on your response to the solution used and your desired level of perfection. You must wait three weeks between treatments when scheduling your procedures. During this time some veins will completely disappear and some will partially disappear. Subsequent treatments will involve re-injecting veins that only partially disappeared (resistant veins) and those we were unable to address in prior treatments. There is a medically safe limit on how much solution you can receive in one treatment, and we will always stay within that limit. Our experience has shown that this safe, conservative approach gives the best possible outcome. 

Step 7

Your vein treatment is completed to your satisfaction. Enjoy your new look!

You will not get these veins back, but if you are genetically predisposed to forming spider and varicose veins, over time you may develop new ones. Our patients return as needed. Some patients return yearly, others may find they can go several years without feeling the need to return.

All medical procedures have some risk of complications or undesirable effects. Please read this area of our website to be fully informed.

The photos below are examples of small veins before and after sclerotherapy.

Reticular Veins behind the knee

Spider Veins -very typical presentation


Spider veins - known in the medical world as telangiectasias or sunburst varicosities- are small, thin veins that lie close to the surface of the skin. Although these super-fine veins are connected with the larger venous system, they are not an essential part of it. In fact, they serve no useful purpose whatsoever, therefore by eliminating them, one need not be concerned about any negative health effects.


Heredity is the number one contributing factor causing varicose and spider veins.  Men and women develop spider veins. Up to 50% of American women may be affected. Hormonal factors including puberty, pregnancy, menopause, the use of birth control pills, estrogen, and progesterone affect the disease.  Other predisposing factors include aging, standing occupations, obesity and leg injury


Today many physicians are treating spider veins with sclerotherapy. In this rather simple procedure which is safe and involves minimal discomfort, veins are injected with a sclerosing solution. The sclerosing agents work by irritating the inside of the vein, so that on compression of the vein with firm support hose, the vein closes and becomes fibrosed. Blood can no longer enter the vein, and then the body will slowly dissolve this nonfunctional vessel and over time it fades from view. By eliminating these dilated surface vessels, the circulation is actually improved. The procedure may also correct the symptoms associated with spider veins including aching, burning, swelling, and night cramps.  Although this procedure has been used in Europe for more than 50 years, it has only become popular in the United States during the past two decades. The introduction of sclerosing agents that are mild enough to be used in small veins has made sclerotherapy predictable and relatively painless. We use an FDA approved solution called Sotradecol in varying strengths depending on the size of the vein to be treated.


The majority of people who have sclerotherapy performed will be cleared of their varicosities or at least see significant improvement. Unfortunately, however, there is no guarantee that sclerotherapy will be effective in every case. Approximately 5 % of patients who undergo sclerotherapy have poor to fair results. “Poor results” means that the veins have not responded after several treatments. In very rare instances, the patient’s condition may become worse after sclerotherapy treatment.


Itching- depending on the type of solution used,  some patients experience mild itching along the vein route. This usually resolves within 2 hours.

Pain -. When larger veins are injected, the veins may be tender to the touch after treatment, and an uncomfortable sensation may run along the vein route. This tenderness is usually temporary and lasts 1 to 7 days. 


Transient hyperpigmentation -  Approximately 30% of patients notice a slight pigmentation irregularity - brownish splotches around the injection site that may take months to fade, sometimes up to a year.  

 Telangiectatic matting -  The development of new, tiny blood vessels close to the site of injection can develop in a small percentage of patients. This usually fades over months.

Sloughing-  Sloughing occurs in less than 3% of patients who receive sclerotherapy. Sloughing may consist of ulceration at the injection site that heals slowly. A blister may form, open, and become ulcerated. The scar that follows should return to a normal color

Allergic reactions - Very rarely, a patient may have an allergic reaction to the sclerosing agent used. The risk of an allergic reaction is greater in patients who have a history of allergies


Most patients are very pleased with the difference sclerotherapy makes. Sclerotherapy can produce excellent results, however, because it is non-surgical and relies on your body to dissolve the undesirable vessel, it takes time to get your final results. Treated vessels may look worse for 7-14 days. Gradual improvement should be seen by 3 weeks with a slow fading continuing for weeks or months. Although sclerotherapy will obliterate the noticeable veins for good, it’s important to remember that treatment will not prevent new spider veins from emerging in the future.


By attending seminars on the latest available technology, Dr. Grisoli stays informed of new laser treatments used to treat spider veins. He has access to the most advanced laser for spider vein treatment at this time, and patients with certain types of spider veins may benefit from this. If you are a candidate, he will tell you so at your evaluation. Sclerotherapy has been shown to produce the most consistent and cost effective results when performed properly.


Consultation is free. Dr.Grisoli charges $300 for each treatment session. A session usually lasts about 30 minutes. Some patients can be completely treated in one session; however the average patient is usually happy after 2-3 sessions. After an initial examination and consultation, he will give you a treatment plan suggesting how many sessions may be necessary. To maximize the cost effectiveness of this procedure to the patient, we do as much as possible at each session and hold the cost to $300.The only other cost you will incur is the price of the medical support hose which is currently $35. Therefore, your initial treatment will total $335 and all subsequent treatments are $300.


Payment is expected at the time of your treatment. Sclerotherapy for small veins is considered a cosmetic procedure and is not covered by insurance companies. For your convenience, payment can be made by cash, check, or credit card (Visa, Mastercharge, American Express, or Discovery).


You will be instructed to wear medically graduated compression hose immediately after your injections. If you already own a pair, you can bring these to your appointment. If you need to purchase a pair, we provide them through our office for $35 a pair. You may purchase them at the time of your appointment.